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Exp Ther Med (2020) 20(4):376674

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The pharmacological antagonists of MC4R appeared to lead to weight gain, while the agonist was observed to lead to the contrary in laboratory experiments

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Examining the downstream mechanisms through which MC1R-cAMP signalling antagonises inflammatory cytokine production and studying how MT-1s anti-inflammatory effects in skin cells contribute to its photoprotective biology beyond melanin-dependent UV absorption